Amyloidosis
Description
amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.
Data source
| FinnGen phenocode | E4_AMYLOIDOSIS |
| Hospital Discharge registry | ICD-10: E85 |
| Cause of Death registry | ICD-10: E85 |
| Include | E4_AMYL_NONNEURO, E4_AMYL_NEUROHER, E4_AMYL_HEREDOFAM, E4_AMYL_SCNDSYST, E4_AMYL_ORGAN, E4_AMYLNAS |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 175 | 98 | 77 |
| Unadjusted prevalence (%) | 0.1 | 0.1 | 0.1 |
| Mean age at first event (years) | 60.37 | 57.8 | 63.64 |
| Case fatality at 5-years (%) | 24.0 | 24.49 | 23.38 |
Longitudinal metrics
| Sex | All | Female | Male |
| Median nb. of events per indiv. | 4 | 4 | 3 |
| Recurrence at 6 months (%) | 57.14 | 59.18 | 54.55 |
Associations
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