Secondary systemic amyloidosis

Description

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Data source
FinnGen phenocode E4_AMYL_SCNDSYST
Hospital Discharge registry ICD-10: E853
Cause of Death registry ICD-10: E853
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 9120
GWAS catalog 1001875
MESH D000686
SNOMED CT 17602002

Key figures

Sex All Female Male
Number of individuals 40 27 13
Unadjusted prevalence (%) 0.02 0.03 0.02
Mean age at first event (years) 61.91 61.25 63.27
Case fatality at 5-years (%) 35.0 44.44 15.38

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 3 3
Recurrence at 6 months (%) 55.0 48.15 69.23

Associations

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