Organ-limited amyloidosis

Description

amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.

Data source
FinnGen phenocode E4_AMYL_ORGAN
Hospital Discharge registry ICD-10: E854
Cause of Death registry ICD-10: E854
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 9120
GWAS catalog 1001875
MESH D000686
SNOMED CT 17602002

Key figures

Sex All Female Male
Number of individuals 26 12 14
Unadjusted prevalence (%) 0.01 0.01 0.02
Mean age at first event (years) 69.62 67.68 71.29
Case fatality at 5-years (%) 57.69 50.0 64.29

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 23.08 33.33 14.29

Associations

Loading associations…