Polyarteritis nodosa and related conditions

Description

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Data source
FinnGen phenocode M13_POLYARTERETAL
Hospital Discharge registry ICD-10: M30
Cause of Death registry ICD-10: M30
Include M13_POLNODOSA, M13_CHURGSTRAUSS, M13_JUVEPOLYNOD, M13_KAWASAKI, M13_POYARTOTH
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9810
GWAS catalog 0009012
MESH D010488

Key figures

Sex All Female Male
Number of individuals 123 79 44
Unadjusted prevalence (%) 0.07 0.08 0.06
Mean age at first event (years) 49.2 48.51 50.45
Case fatality at 5-years (%) 9.76 7.59 13.64

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 39.02 43.04 31.82

Associations

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