Polyarteritis nodosa

Description

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Data source
FinnGen phenocode M13_POLNODOSA
Hospital Discharge registry ICD-10: M300, ICD-9: 4460A, ICD-8: 4460
Cause of Death registry ICD-10: M300, ICD-9: 4460A, ICD-8: 4460
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 9810
GWAS catalog 0009012
MESH D010488

Key figures

Sex All Female Male
Number of individuals 67 41 26
Unadjusted prevalence (%) 0.04 0.04 0.03
Mean age at first event (years) 54.29 54.18 54.45
Case fatality at 5-years (%) 16.42 12.2 23.08

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 23.88 34.15 7.69

Associations

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