Glaucoma

Description

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Data source
FinnGen phenocode H7_GLAUCOMA
Hospital Discharge registry ICD-10: H42/H40
Cause of Death registry ICD-10: H40/H42
Include H7_GLAUCSUSP, H7_GLAUCPRIMOPEN, H7_GLAUCCLOSEPRIM, H7_GLAUCSECTRAUMA, H7_GLAUCSECINFLAM, H7_GLAUCSECDISEASE, H7_GLAUCSECDRUG, H7_GLAUCNAS, H7_GLAUCOMAMEDICATION, H7_GLAUCINOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 1686
GWAS catalog 0000516
MESH D005901
SNOMED CT 23986001

Key figures

Sex All Female Male
Number of individuals 6537 3940 2597
Unadjusted prevalence (%) 3.75 3.97 3.46
Mean age at first event (years) 62.42 62.37 62.5
Case fatality at 5-years (%) 3.69 2.84 4.97

Heritability

SNP-h2 liability CI
0.12 [0.07, 0.18]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 3 3
Recurrence at 6 months (%) 51.87 50.38 54.07

First-event distributions

Associations

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