Finngen Rheumatological endpoints

Description

rheumatic disease: Inflammatory and degenerative diseases of connective tissue structures, such as arthritis.

Data source
FinnGen phenocode RHEUMA_ENDPOINTS
Include RHEUMA_ARHTROPAT_REACTIVE, RHEUMA_SEROPOS, RHEUMA_SERONEG, JUVEN_ARTHR, PSOR_ENTE_ARTHR, GOUT, RHEUMA_CHRYSTAL, ARTHRO_SPEC, RHEU_ARTHRITIS_OTH, COX_ARTHROSIS, KNEE_ARTHROSIS, SLE_FG, NECROVASC_FG, DERMATOPOLY_FG, SYSTSCLE_FG, OTHER_SYSTCON_FG, SYSTINOTH_FG, SPONDYLOPATHY_FG, M13_FIBROMYALGIA, OSTEOPOROSIS_FRACTURE_FG
First defined in version DF2
Ontology
DOID 1575
GWAS catalog 0005755
MESH D012216
SNOMED CT 396332003

Key figures

Sex All Female Male
Number of individuals 35023 20876 14147
Unadjusted prevalence (%) 20.09 21.05 18.83
Mean age at first event (years) 55.55 55.14 56.15
Case fatality at 5-years (%) 2.54 1.92 3.45

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 3 3
Recurrence at 6 months (%) 58.03 60.89 53.8

Associations

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