Spondylopathies

Description

ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Data source
FinnGen phenocode M13_SPONDYLOPATHY
Hospital Discharge registry ICD-10: M48/M46/M45/M47
Cause of Death registry ICD-10: M48/M47/M45/M46
Include M13_ANKYLOSPON, M13_SPINENTHES, M13_SACROILIITIS, M13_OSTEOMYELVERTEB, M13_DISCINFECTION, M13_DISCITIS, M13_SPONDYLOINFECTION, M13_SPONDYLINFLAMNAS, M13_SPONDYLOSIS, M13_SPINSTENOSIS, M13_FORESTIER, M13_KISSING, M13_SPONDYLOTRAUM, M13_FATIGFRACT, M13_VERTEBCOLLAPSE, M13_SPONDYLOPATHYNAS, M13_SPONDYLOPATHINOTH
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 7147
GWAS catalog 0003898
MESH D013122
SNOMED CT 9631008

Key figures

Sex All Female Male
Number of individuals 14006 7849 6157
Unadjusted prevalence (%) 8.03 7.91 8.19
Mean age at first event (years) 57.69 57.8 57.53
Case fatality at 5-years (%) 2.68 2.03 3.51

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 2
Recurrence at 6 months (%) 53.07 53.21 52.88

Associations

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