Ankylosing spondylitis


ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Data source
FinnGen phenocode M13_ANKYLOSPON
Hospital Discharge registry ICD-10: M45, ICD-8: 7124
Cause of Death registry ICD-10: M45, ICD-8: 7124
Level in the ICD-hierarchy 4
First defined in version DF2
DOID 7147
GWAS catalog 0003898
MESH D025242
SNOMED CT 9631008

Key figures

Sex All Female Male
Number of individuals 1103 525 578
Unadjusted prevalence (%) 0.63 0.53 0.77
Mean age at first event (years) 42.48 42.84 42.16
Case fatality at 5-years (%) 0.82 0.95 0.69

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 5 4 5
Recurrence at 6 months (%) 63.55 62.48 64.53

First-event distributions


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