Osteopathies and chondropathies
Description
secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)
Data source
| FinnGen phenocode | M13_OSTEOCHONDRO |
| Hospital Discharge registry | ICD-10: M93/M91/M92/M94 |
| Cause of Death registry | ICD-10: M92/M94/M93/M91 |
| Include | M13_OSTEOPOROSIS, M13_OSTEOMALACIA, M13_BONECONTINUITY, M13_BONEDENSOTH, M13_OSTEOMYELITIS, M13_OSTEONECROSIS, M13_PAGET, M13_OTHERBONE |
| Level in the ICD-hierarchy | 2 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 7041 | 4427 | 2614 |
| Unadjusted prevalence (%) | 4.04 | 4.46 | 3.48 |
| Mean age at first event (years) | 50.98 | 53.74 | 46.3 |
| Case fatality at 5-years (%) | 5.77 | 5.87 | 5.59 |
Heritability
| SNP-h2 liability | CI |
| 0.05 | [0.0, 0.1] |
Longitudinal metrics
| Sex | All | Female | Male |
| Median nb. of events per indiv. | 1 | 1 | 1 |
| Recurrence at 6 months (%) | 32.78 | 33.53 | 31.52 |
Associations
Loading associations…