Disorders of lens

Description

cataract: Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)

Data source
FinnGen phenocode H7_LENS
Hospital Discharge registry ICD-10: H27/H25/H28/H26
Cause of Death registry ICD-10: H28/H27/H26/H25
Include H7_CATARACTSENILE, H7_CATARACTOTHER, H7_APHAKIA, H7_LENSDISLOCATIO, H7_DISORDERLENSNAS
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 83
GWAS catalog 0001059
MESH D007905
SNOMED CT 193570009

Key figures

Sex All Female Male
Number of individuals 21994 12927 9067
Unadjusted prevalence (%) 12.62 13.03 12.07
Mean age at first event (years) 69.27 69.66 68.72
Case fatality at 5-years (%) 7.18 5.73 9.25

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 2
Recurrence at 6 months (%) 37.84 37.77 37.95

Associations

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