Hyperfunction of pituitary gland

Description

hyperpituitarism: Disease of the glandular, anterior portion of the pituitary (pituitary gland, anterior) resulting in hypersecretion of adenohypophyseal hormones such as growth hormone; prolactin; thyrotropin; luteinizing hormone; follicle stimulating hormone ; and adrenocorticotropic hormone. Hyperpituitarism usually is caused by a functional adenoma.

Data source
FinnGen phenocode E4_HYPERPIT
Hospital Discharge registry ICD-10: E22
Cause of Death registry ICD-10: E22
Include E4_ACROMEG, E4_HYPERPRO, E4_ANTIDIU, E4_HYPERPITNAS
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2444
GWAS catalog 1000973
MESH D006964
SNOMED CT 10649000

Key figures

Sex All Female Male
Number of individuals 585 472 113
Unadjusted prevalence (%) 0.34 0.48 0.15
Mean age at first event (years) 39.17 36.74 49.32
Case fatality at 5-years (%) 0.85 0.85 0.88

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 2 3
Recurrence at 6 months (%) 54.36 52.54 61.95

Associations

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