Other coagulation defects

Description

thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Data source
FinnGen phenocode D3_COAGOTHER
Hospital Discharge registry ICD-10: D68
Cause of Death registry ICD-10: D68
Include D3_VONVILLEBRAND, D3_HEREDFXIDEF, D3_HEREDOTHCLOFACTORS, D3_HAEMORRHAGCIRGUANTICO, D3_ACQCOAFACDEF, D3_PRIMTHROMBOPHILIA, D3_OTHTHROMBOPHILIA, D3_COAGDEFNAS
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2452
GWAS catalog 0009315
MESH D001778
SNOMED CT 234467004

Key figures

Sex All Female Male
Number of individuals 659 441 218
Unadjusted prevalence (%) 0.38 0.44 0.29
Mean age at first event (years) 48.06 44.83 54.6
Case fatality at 5-years (%) 11.68 6.35 22.48

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 2 1
Recurrence at 6 months (%) 36.57 41.5 26.61

Associations

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