Systemic sclerosis,strict definition

Description

scleroderma: Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc) (see these terms).

Data source
FinnGen phenocode SYSTSCLE_STRICT
KELA reimboursements codes ANY
KELA reimbursements ICD-10: M34
Conditions required SYSTSCLE_ICD10
First defined in version DF3
Ontology
DOID 419
GWAS catalog 1001993
MESH D012595

Key figures

Sex All Female Male
Number of individuals 71 62 9
Unadjusted prevalence (%) 0.04 0.06 0.01
Mean age at first event (years) 53.85 53.8 54.18
Case fatality at 5-years (%) 4.23 3.23 11.11

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) - - -

Associations

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