Seropositive rheumatoid arthritis, strict definition

Description

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Data source
FinnGen phenocode RHEUMA_SEROPOS_STRICT
KELA reimboursements codes ANY
KELA reimbursements ICD-10: M058/M059
Conditions required RHEUMA_SEROPOS_OTH_ICD10
First defined in version DF3
Ontology
DOID 11042
GWAS catalog 0007269
MESH D001172
SNOMED CT 57160007

Key figures

Sex All Female Male
Number of individuals 788 549 239
Unadjusted prevalence (%) 0.45 0.55 0.32
Mean age at first event (years) 57.95 56.78 60.64
Case fatality at 5-years (%) 1.02 0.73 1.67

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 2.34 2.72 1.43

Associations

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