Symptoms and signs involving the skin and subcutaneous tissue

Description

exanthem: a widespread rash usually occurring in children but can occur in adults. An exanthem can be caused by toxins, drugs, or microorganisms, or can result from autoimmune disease. It can be contrasted with an enanthem.

Data source
FinnGen phenocode R18_SYMPTOMS_SIGNS_INVOLVI_SKIN_SUBCU_TISSUE
Hospital Discharge registry ICD-10: R22/R21/R20/R23
Cause of Death registry ICD-10: R20/R22/R23/R21
Include R18_DISTU_SKIN_SENSA, R18_RASH_OTHER_NONSPECIFIC_SKIN_ERUPT, R18_LOCALIZED_SWELL_MASS_LUMP_SKIN_SUBCU_TISSUE, R18_OTHER_SKIN_CHANG
Level in the ICD-hierarchy 2
First defined in version DF4
Ontology
DOID 0050486
GWAS catalog 1000697
MESH D012877
SNOMED CT 271807003

Key figures

Sex All Female Male
Number of individuals 8274 5214 3060
Unadjusted prevalence (%) 4.75 5.26 4.07
Mean age at first event (years) 53.07 51.01 56.59
Case fatality at 5-years (%) 2.67 1.67 4.38

Heritability

SNP-h2 liability CI
0.04 [0.0, 0.08]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 21.44 22.11 20.29

Associations

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