Systemic lupus erythematosus

Description

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Data source
FinnGen phenocode M13_SLE
Hospital Discharge registry ICD-10: M32, ICD-8: 7431
Cause of Death registry ICD-10: M32, ICD-8: 7431
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9074
GWAS catalog 0002690
MESH D008180
SNOMED CT 55464009

Key figures

Sex All Female Male
Number of individuals 417 349 68
Unadjusted prevalence (%) 0.24 0.35 0.09
Mean age at first event (years) 46.35 45.78 49.26
Case fatality at 5-years (%) 3.36 3.44 2.94

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 5 6 4
Recurrence at 6 months (%) 65.23 65.33 64.71

Associations

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