Coxarthrosis,

PheWeb

Description

osteoarthritis: A noninflammatory degenerative joint disease occurring chiefly in older persons, characterised by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity.

Data source

FinnGen phenocode	M13_ARTHTROSIS_COX
Hospital Discharge registry	ICD-10: M16, ICD-9: 7151E/7152E, ICD-8: 71300
Cause of Death registry	ICD-10: M16, ICD-9: 7151E/7152E, ICD-8: 71300
Level in the ICD-hierarchy	4
First defined in version	DF2

Ontology

DOID	8398
GWAS catalog	0002506
MESH	D015207

Key figures

Sex	All	Female	Male
Number of individuals	7950	4488	3462
Unadjusted prevalence (%)	4.56	4.53	4.61
Mean age at first event (years)	63.04	63.29	62.72
Case fatality at 5-years (%)	2.86	2.45	3.38

Heritability

SNP-h² liability	CI
0.11	[0.06, 0.16]

Longitudinal metrics

Sex	All	Female	Male
Median nb. of events per indiv.	3	3	3
Recurrence at 6 months (%)	63.76	63.35	64.3

Associations

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