Radiation-related disorders of the skin and subcutaneous tissue

Description

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Data source
FinnGen phenocode L12_RADIATIONRELATEDSKIN
Hospital Discharge registry ICD-10: L59/L55/L58/L56/L57
Cause of Death registry ICD-10: L55/L57/L59/L58/L56
Include L12_SUNBURN, L12_OTHACUSKINSUN, L12_NONIONRADISKIN, L12_RADIODERMATITIS, L12_SKINRADIOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 3818, 4407
GWAS catalog 1000753
MESH D010787
SNOMED CT 53597009

Key figures

Sex All Female Male
Number of individuals 4017 2225 1792
Unadjusted prevalence (%) 2.3 2.24 2.38
Mean age at first event (years) 66.82 66.4 67.33
Case fatality at 5-years (%) 5.15 4.67 5.75

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 2
Recurrence at 6 months (%) 41.55 38.11 45.81

Associations

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