Dermatitis herpetiformis

Description

dermatitis herpetiformis: Dermatitis herpetiformis (DH) is a chronic autoimmune subepidermal bullous disease characterized by grouped pruritic lesions such as papules, urticarial plaques, erythema, and herpetiform vesiculae, with a predominantly symmetrical distribution on extensor surfaces of the elbows (90%), knees (30%), shoulders, buttocks, sacral region, and face of children and adults. Erosions, excoriations and hyperpigmentation usually follow. DH may also appear as a consequence of gluten intolerance.

Data source
FinnGen phenocode L12_DERMATHERP
Hospital Discharge registry ICD-10: L130, ICD-9: 6940A, ICD-8: 693
Cause of Death registry ICD-10: L130, ICD-9: 6940A, ICD-8: 693
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 8505
GWAS catalog 1000684
MESH D003874
SNOMED CT 111196000

Key figures

Sex All Female Male
Number of individuals 218 129 89
Unadjusted prevalence (%) 0.13 0.13 0.12
Mean age at first event (years) 45.33 43.37 48.16
Case fatality at 5-years (%) 1.38 0.78 2.25

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 1 3
Recurrence at 6 months (%) 41.28 36.43 48.31

Associations

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