Pneumoconiosis due to dust containing silica

Description

silicosis: Silicosis is a respiratory disease caused by breathing in (inhaling) silica dust. There are three types of silicosis: Simple chronic silicosis, the most common type of silicosis, results from long-term exposure (usually more than 20years) to low amounts of silica dust. Simple chronic silicosismay causepeople to have difficulty breathing. Accelerated silicosis occurs after 5 to 15 yearsof exposure of higher levels of silica.Swelling of the lungsand other symptoms occur faster in this type of silicosis than in the simple chronic form. Acute silicosis results from short-term exposure (weeks or months) of large amounts of silica.The lungs become very inflamed and can fill with fluid, causing severe shortness of breath and low blood oxygen levels. A cough, weight loss, and fatigue may also be present. Acute silicosis progresses rapidly and can be fatal within months. People who work in jobs where they are exposed to silica dust (mining, quarrying, construction, sand blasting, stone cutting) are at risk of developing this condition.

Data source
FinnGen phenocode J10_SILICAPNEUMOC
Hospital Discharge registry ICD-10: J62, ICD-9: 502, ICD-8: 5150
Cause of Death registry ICD-10: J62, ICD-9: 502, ICD-8: 5150
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 10325
GWAS catalog 0007485
MESH D012829
SNOMED CT 805002

Key figures

Sex All Female Male
Number of individuals 23 6 17
Unadjusted prevalence (%) 0.01 0.01 0.02
Mean age at first event (years) 57.21 55.16 57.93
Case fatality at 5-years (%) 13.04 0.0 17.65

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 2
Recurrence at 6 months (%) 34.78 16.67 41.18

Associations

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