ILD-related respiratory insufficiency

Description

respiratory failure: The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. [NCIT:C26872]

Data source
FinnGen phenocode ILD_INSUFFICIENCY
Include RESPIRATORYINSUFF, CPAP, NIV, I9_SECONDRIGHT
First defined in version DF2
Ontology
DOID 11162
GWAS catalog 0009686
MESH D012131
SNOMED CT 39871006

Key figures

Sex All Female Male
Number of individuals 3614 1460 2154
Unadjusted prevalence (%) 2.07 1.47 2.87
Mean age at first event (years) 63.5 63.01 63.83
Case fatality at 5-years (%) 14.47 14.38 14.53

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 16.94 18.08 16.17

Associations

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