ILD differential diagnosis

Description

interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.

Data source
FinnGen phenocode ILD_DIFF_DG
Include RESPIRATORYINSUFF, J10_COPDNAS, ASTHMA_MODE, J10_BRONCHIECTASIS, D3_SARCOIDOSIS, TUBERCULOSIS, RESPIRATORYINSUFF, J10_EMPHYSEMA, J10_BRONCHNAS, LUNG_CANCER_MESOT, PULMONARYDG, ESOSINOPHIL_DISEASE
First defined in version DF2
Ontology
DOID 3082
GWAS catalog 0004244
MESH D017563
SNOMED CT 233703007

Key figures

Sex All Female Male
Number of individuals 63213 34583 28630
Unadjusted prevalence (%) 36.26 34.87 38.1
Mean age at first event (years) 46.57 44.97 48.51
Case fatality at 5-years (%) 6.71 4.88 8.93

Heritability

SNP-h2 liability CI
0.04 [0.02, 0.05]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 2
Recurrence at 6 months (%) 43.47 43.03 44.01

Associations

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