Rheumatic fever incl heart disease
Description
rheumatic fever: Rheumatic fever (RF) is a multisystem inflammatory disease occurring as a post-infectious, nonsuppurative sequela of untreated streptococcus pyogenes (Group A streptococcus [GAS]) pharyngitis, and mainly occurs in individuals aged 5 to 15 years. The most common presenting signs are fever, migratory polyarthritis and carditis.
Data source
| FinnGen phenocode | I9_RHEUFEV |
| Include | I9_RHEUFEVHRT, I9_RHEUFEVWITHOUTHEART, I9_RHEUVALV, I9_RHEUOTHHRT |
| Level in the ICD-hierarchy | 2 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 462 | 232 | 230 |
| Unadjusted prevalence (%) | 0.27 | 0.23 | 0.31 |
| Mean age at first event (years) | 48.44 | 48.01 | 48.87 |
| Case fatality at 5-years (%) | 10.17 | 9.91 | 10.43 |
Longitudinal metrics
| Sex | All | Female | Male |
| Median nb. of events per indiv. | 1 | 1 | 1 |
| Recurrence at 6 months (%) | 16.23 | 14.66 | 17.83 |
Associations
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