Peripheral artery disease

Description

peripheral arterial disease: A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest.

Data source
FinnGen phenocode I9_PAD
Hospital Discharge registry ICD-10: E135/I739/E115/E105/E145/I702/E125, ICD-8: 25006|4402|4439
Cause of Death registry ICD-10: E135/I739/E115/E105/E145/I702/E125, ICD-8: 25006|4402|4439
Include I9_PERIPH
Level in the ICD-hierarchy C
First defined in version DF2
Ontology
DOID 0050830
GWAS catalog 0004265
MESH D058729
SNOMED CT 399957001

Key figures

Sex All Female Male
Number of individuals 5323 1975 3348
Unadjusted prevalence (%) 3.05 1.99 4.46
Mean age at first event (years) 65.19 66.42 64.46
Case fatality at 5-years (%) 15.25 15.7 14.99

Heritability

SNP-h2 liability CI
0.06 [0.01, 0.12]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 2
Recurrence at 6 months (%) 55.52 52.94 57.05

Associations

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