Non-rheumatic valve diseases

Description

heart valve disease: A disease involving the cardial valve.

Data source
FinnGen phenocode I9_NONRHEVALV
Hospital Discharge registry ICD-10: I37/I36/I35/I34, ICD-9: 424, ICD-8: 39[4-6]|424
Hospital Discharge registry: exclude ICD-8 4249|3940|3950|3960|3970
Cause of Death registry ICD-10: I35/I37/I34/I36, ICD-9: 424, ICD-8: 39[4-6]|424
Cause of Death registry: exclude ICD-8 4249|3940|3950|3960|3970
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 4079
GWAS catalog 0009551
MESH D006349
SNOMED CT 368009

Key figures

Sex All Female Male
Number of individuals 7440 3440 4000
Unadjusted prevalence (%) 4.27 3.47 5.32
Mean age at first event (years) 64.82 65.17 64.52
Case fatality at 5-years (%) 9.92 8.92 10.78

Heritability

SNP-h2 liability CI
0.05 [0.01, 0.1]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 2 3
Recurrence at 6 months (%) 45.6 40.22 50.22

Associations

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