Heart failure,strict

Description

systolic heart failure: Heart failure caused by abnormal myocardial contraction during systole leading to defective cardiac emptying.

Data source
FinnGen phenocode I9_HEARTFAIL
Hospital Discharge registry ICD-10: I50/I110/I132/I130, ICD-9: 4029B/428, ICD-8: 42700|42710|428|7824
Cause of Death registry ICD-10: I130/I110/I50/I132, ICD-9: 4029B/404/428, ICD-8: 42700|42710|428
KELA reimboursements codes 201
Medicine purchases: ATC; other reg. data required YES
Medicine purchases: ATC codes C03CA01|C03EB01
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9651
GWAS catalog 1001207
MESH D006333
SNOMED CT 417996009

Key figures

Sex All Female Male
Number of individuals 9576 4199 5377
Unadjusted prevalence (%) 5.49 4.23 7.16
Mean age at first event (years) 66.47 68.02 65.25
Case fatality at 5-years (%) 18.09 16.86 19.04

Heritability

SNP-h2 liability CI
0.05 [0.01, 0.08]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 4 4 5
Recurrence at 6 months (%) 64.4 61.9 67.22

Associations

Loading associations…