Cerebral atherosclerosis

Description

cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Data source
FinnGen phenocode I9_CEREBATHER
Hospital Discharge registry ICD-10: I672, ICD-8: 437
Cause of Death registry ICD-10: I672, ICD-8: 437
First defined in version DF2
Ontology
DOID 12720
GWAS catalog 1000860
MESH D002537
SNOMED CT 55382008

Key figures

Sex All Female Male
Number of individuals 86 42 44
Unadjusted prevalence (%) 0.05 0.04 0.06
Mean age at first event (years) 68.9 69.2 68.61
Case fatality at 5-years (%) 37.21 33.33 40.91

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 11.63 7.14 15.91

Associations

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