Cerebral atherosclerosis


cerebral atherosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Data source
FinnGen phenocode I9_CEREBATHER
Hospital Discharge registry ICD-10: I672, ICD-8: 437
Cause of Death registry ICD-10: I672, ICD-8: 437
First defined in version DF2
DOID 12720
GWAS catalog 1000860
MESH D002537
SNOMED CT 55382008

Key figures

Sex All Female Male
Number of individuals 86 42 44
Unadjusted prevalence (%) 0.05 0.04 0.06
Mean age at first event (years) 68.9 69.2 68.61
Case fatality at 5-years (%) 37.21 33.33 40.91

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 11.63 7.14 15.91


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