Cerebral amyloid angiopathy

Description

cerebral amyloid angiopathy: Hereditary cerebral hemorrhage with amyloidosis (HCHWA) describes a group of rare familial central nervous system disorders characterized by amyloid deposition in the cerebral blood vessels leading to hemorrhagic and non-hemorrhagic strokes, focal neurological deficits, and progressive cognitive decline eventually leading to dementia.

Data source
FinnGen phenocode I9_CEREBAMY
Hospital Discharge registry ICD-10: I680
Cause of Death registry ICD-10: I680
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9246
GWAS catalog 0006790
MESH D016657
SNOMED CT 230724001

Key figures

Sex All Female Male
Number of individuals 17 - 12
Unadjusted prevalence (%) 0.01 - 0.02
Mean age at first event (years) 65.71 - 65.9
Case fatality at 5-years (%) 17.65 - 8.33

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 - 1
Recurrence at 6 months (%) 11.76 - 16.67

Associations

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