Angina pectoris


Prinzmetal's angina: a syndrome typically consisting of angina (cardiac chest pain) at rest that occurs in cycles. It is caused by vasospasm, a narrowing of the coronary arteries caused by contraction of the smooth muscle tissue in the vessel walls rather than directly by atherosclerosis (buildup of fatty plaque and hardening of the arteries). For a portion of patients Prinzmetal's angina may be a manifestation of vasospastic disorder and is associated with migraine, Raynaud's phenomenon or aspirin-induced asthma.

Data source
FinnGen phenocode I9_ANGINA
Hospital Discharge registry ICD-10: I20, ICD-9: 413, ICD-8: 413
Cause of Death registry ICD-10: I20, ICD-9: 413, ICD-8: 413
Level in the ICD-hierarchy 3
First defined in version DF2
DOID 0111151
GWAS catalog 1000013
MESH D000787
SNOMED CT 87343002

Key figures

Sex All Female Male
Number of individuals 14712 5661 9051
Unadjusted prevalence (%) 8.44 5.71 12.04
Mean age at first event (years) 62.28 64.22 61.07
Case fatality at 5-years (%) 6.62 6.68 6.58

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 30.32 25.68 33.22


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