Cholesteatoma of middle ear

Description

cholesteatoma of middle ear: A non-neoplastic lesion characterized by the proliferation of keratinizing squamous epithelium in the middle ear that results in the accumulation of keratin and cells. It is usually caused by repeated infections. If left untreated, it may increase in size and destroy the adjacent delicate bones of the middle ear.

Data source
FinnGen phenocode H8_CHOLEASTOMA
Hospital Discharge registry ICD-10: H71, ICD-8: 38700
Cause of Death registry ICD-10: H71, ICD-8: 38700
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 10964, 11433
GWAS catalog 1000678
MESH D018424
SNOMED CT 194339007

Key figures

Sex All Female Male
Number of individuals 630 299 331
Unadjusted prevalence (%) 0.36 0.3 0.44
Mean age at first event (years) 46.13 45.47 46.74
Case fatality at 5-years (%) 1.75 1.67 1.81

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 4 4 4
Recurrence at 6 months (%) 50.32 50.5 50.15

Associations

Loading associations…