Disorders of sclera, cornea, iris and ciliary body

Description

corneal neovascularization: New blood vessels originating from the corneal veins and extending from the limbus into the adjacent corneal stroma. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as trachoma, viral interstitial keratitis, microbial keratoconjunctivitis, and the immune response elicited by corneal transplantation.

Data source
FinnGen phenocode H7_SCLERACORNEA
Hospital Discharge registry ICD-10: H16/H15/H22/H20/H17/H18/H21
Cause of Death registry ICD-10: H17/H18/H15/H22/H21/H16/H20
Include H7_SCLERITISEPISCLERITIS, H7_SCLERANAS, H7_KERATITIS, H7_CORNEALOTH, H7_IRIDOCYCLITIS, H7_OTHIRISCILIARY
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 11382
GWAS catalog 1000880
MESH D014603
SNOMED CT 19161004

Key figures

Sex All Female Male
Number of individuals 7295 4070 3225
Unadjusted prevalence (%) 4.18 4.1 4.29
Mean age at first event (years) 49.16 49.27 49.02
Case fatality at 5-years (%) 2.67 2.11 3.38

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 26.96 27.89 25.8

Associations

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