Optic neuritis

Description

optic neuritis: Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.The conditionmay cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis , drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.

Data source
FinnGen phenocode H7_OPTNEURITIS
Hospital Discharge registry ICD-10: H46, ICD-8: 3670[2-9]
Cause of Death registry ICD-10: H46, ICD-8: 3670[2-9]
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 1210
GWAS catalog 0007405
MESH D009902
SNOMED CT 66760008

Key figures

Sex All Female Male
Number of individuals 451 338 113
Unadjusted prevalence (%) 0.26 0.34 0.15
Mean age at first event (years) 40.1 39.38 42.28
Case fatality at 5-years (%) 1.55 1.78 0.88

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 37.69 38.46 35.4

Associations

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