Postpolio syndrome

Description

postpoliomyelitis syndrome: Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis (see this term), 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing.

Data source
FinnGen phenocode G6_POSTPOLIO
Hospital Discharge registry ICD-10: G14, ICD-9: 138, ICD-8: 4499
Cause of Death registry ICD-10: G14, ICD-9: 138, ICD-8: 4499
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 4952
GWAS catalog 0007454
MESH D016262
SNOMED CT 31097004

Key figures

Sex All Female Male
Number of individuals 34 20 14
Unadjusted prevalence (%) 0.02 0.02 0.02
Mean age at first event (years) 49.6 49.11 50.31
Case fatality at 5-years (%) 0.0 0.0 0.0

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 8.82 10.0 7.14

Associations

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