MS-disease / Multiple Sclerosis

Description

multiple sclerosis: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.

Data source
FinnGen phenocode G6_MS
Hospital Discharge registry ICD-10: G35, ICD-9: 340, ICD-8: 34099
Cause of Death registry ICD-10: G35, ICD-9: 340, ICD-8: 34099
KELA reimboursements codes 109
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2377
GWAS catalog 0003885
MESH D009103
SNOMED CT 24700007

Key figures

Sex All Female Male
Number of individuals 805 620 185
Unadjusted prevalence (%) 0.46 0.63 0.25
Mean age at first event (years) 40.37 39.22 44.22
Case fatality at 5-years (%) 1.37 0.65 3.78

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 14 14 12
Recurrence at 6 months (%) 77.64 79.19 72.43

First-event distributions

Associations

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