Dementia

Description

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

Data source
FinnGen phenocode F5_DEMENTIA
Hospital Discharge registry ICD-10: F01/F03, ICD-9: 290/4378A, ICD-8: 290
Cause of Death registry ICD-10: F03/F01, ICD-9: 290/4378A, ICD-8: 290
KELA reimboursements codes 307
Medicine purchases: ATC codes N06D
Include F5_ALZHDEMENT, F5_VASCDEM, F5_DEMINOTH, F5_DEMNAS
Level in the ICD-hierarchy 3
First defined in version DF3
Ontology
DOID 1307
GWAS catalog 0003862
MESH D003704

Key figures

Sex All Female Male
Number of individuals 5675 3159 2516
Unadjusted prevalence (%) 3.26 3.19 3.35
Mean age at first event (years) 76.79 77.71 75.64
Case fatality at 5-years (%) 30.87 28.93 33.31

Heritability

SNP-h2 liability CI
0.05 [0.0, 0.1]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 6 6 6
Recurrence at 6 months (%) 74.64 74.44 74.89

Associations

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