Mental and behavioural disorders due to alcohol, excluding acute intoxication

Description

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

Data source
FinnGen phenocode F5_ALCOHOL
Hospital Discharge registry ICD-10: F10, ICD-9: 291/303, ICD-8: 291
Hospital Discharge registry: exclude ICD-10 F100
Cause of Death registry ICD-10: F10, ICD-9: 291/303, ICD-8: 291
Cause of Death registry: exclude ICD-10 F101
Include F5_ALCOHOLAC, F5_ALCOHOL_DEPENDENCE
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2468
GWAS catalog 0005407
MESH D020268
SNOMED CT 69322001

Key figures

Sex All Female Male
Number of individuals 8474 2718 5756
Unadjusted prevalence (%) 4.86 2.74 7.66
Mean age at first event (years) 43.13 40.8 44.23
Case fatality at 5-years (%) 6.24 3.57 7.51

Heritability

SNP-h2 liability CI
0.05 [0.01, 0.1]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 1 2
Recurrence at 6 months (%) 32.45 30.94 33.17

Associations

Loading associations…