Thyrotoxicosis with toxic single thyroid nodule

Description

Hyperthyroidism: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.

Data source
FinnGen phenocode E4_THYTOXNOD
Hospital Discharge registry ICD-10: E051
Cause of Death registry ICD-10: E051
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 7998
GWAS catalog 0009189
MESH D006980
SNOMED CT 34486009

Key figures

Sex All Female Male
Number of individuals 93 82 11
Unadjusted prevalence (%) 0.05 0.08 0.01
Mean age at first event (years) 50.6 49.09 61.89
Case fatality at 5-years (%) 3.23 3.66 0.0

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 27.96 30.49 9.09

Associations

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