Later onset COPD

Description

chronic obstructive pulmonary disease: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.

Data source
FinnGen phenocode COPD_LATER
Hospital Discharge registry ICD-10: J44, ICD-8: 49104
Cause of Death registry ICD-10: J44, ICD-8: 49104
Pre-conditions required EVENT_AGE>=65
Conditions required !COPD_EARLY
First defined in version DF2
Ontology
DOID 3083
GWAS catalog 0000341
MESH D029424
SNOMED CT 13645005

Key figures

Sex All Female Male
Number of individuals 2271 669 1602
Unadjusted prevalence (%) 1.3 0.67 2.13
Mean age at first event (years) 73.05 73.09 73.03
Case fatality at 5-years (%) 27.87 21.23 30.65

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 2 2 2
Recurrence at 6 months (%) 53.85 52.86 54.28

Associations

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