Chronic myeloproliferative disease

Description

chronic myeloproliferative disorder: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)

Data source
FinnGen phenocode CHRONMYELOPRO
Hospital Discharge registry ICD-10: D471
Cause of Death registry ICD-10: D471
First defined in version DF2, additional
Ontology
DOID 2226
GWAS catalog 0002428
SNOMED CT 425333006

Key figures

Sex All Female Male
Number of individuals 86 39 47
Unadjusted prevalence (%) 0.05 0.04 0.06
Mean age at first event (years) 64.03 63.8 64.22
Case fatality at 5-years (%) 15.12 12.82 17.02

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 3 3 3
Recurrence at 6 months (%) 62.79 56.41 68.09

Associations

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