Multiple myeloma and malignant plasma cell neoplasms


multiple myeloma: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)

Data source
Hospital Discharge registry ICD-10: C90, ICD-9: 203, ICD-8: 203
Cause of Death registry ICD-10: C90, ICD-9: 203, ICD-8: 203
Level in the ICD-hierarchy 3
First defined in version DF4
DOID 9538
GWAS catalog 0001378
MESH D009101

Key figures

Sex All Female Male
Number of individuals 418 202 216
Unadjusted prevalence (%) 0.24 0.2 0.29
Mean age at first event (years) 64.64 64.09 65.15
Case fatality at 5-years (%) 24.88 22.77 26.85

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 4 4 4
Recurrence at 6 months (%) 62.92 62.38 63.43


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