Carcinoma in situ of breast, lobular

Description

breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.

Data source
FinnGen phenocode CD2_INSITU_BREAST_LOBULAR
Sex specific endpoint 2
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 0060074, 8791
GWAS catalog 0000432
MESH D000071960

Key figures

Sex All Female Male
Number of individuals 57 57 -
Unadjusted prevalence (%) 0.03 0.06 -
Mean age at first event (years) 58.76 58.76 -
Case fatality at 5-years (%) 1.75 1.75 -

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 -
Recurrence at 6 months (%) 18.97 19.3 -

Associations

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