Brain glioblastoma

Description

brain glioblastoma: A WHO grade IV malignant astrocytic tumor that arises from the brain, usually the cerebral hemispheres. It is characterized by the presence of poorly differentiated astrocytes, cellular polymorphism, nuclear atypia, and increased mitotic activity. The prognosis is poor.

Data source
FinnGen phenocode C3_GBM
Cause of Death registry ICD-10: C71, ICD-9: 191, ICD-8: 191
Cancer reg: TOPOGRAPHY codes C71
Cancer reg: MORPHOLOGY codes 9440
Conditions required HLP_C3_GBM
Level in the ICD-hierarchy C
First defined in version DF4
Ontology
DOID 3073
GWAS catalog 0006545
MESH D005909
SNOMED CT 276828006

Key figures

Sex All Female Male
Number of individuals 70 33 37
Unadjusted prevalence (%) 0.04 0.03 0.05
Mean age at first event (years) 64.68 67.9 61.8
Case fatality at 5-years (%) 68.57 66.67 70.27

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 10.48 12.28 8.96

Associations

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