Malignant neoplasm of corpus uteri

Description

endometrial carcinoma: A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation.

Data source
FinnGen phenocode C3_CORPUS_UTERI
Cause of Death registry ICD-10: C54, ICD-9: 182, ICD-8: 1820
Cancer reg: TOPOGRAPHY codes C54
Sex specific endpoint 2
Level in the ICD-hierarchy 3
First defined in version DF4
Ontology
DOID 2871
GWAS catalog 1001512
MESH D016889
SNOMED CT 254878006

Key figures

Sex All Female Male
Number of individuals 879 879 -
Unadjusted prevalence (%) 0.5 0.89 -
Mean age at first event (years) 63.4 63.4 -
Case fatality at 5-years (%) 7.74 7.74 -

Heritability

SNP-h2 liability CI
0.22 [0.02, 0.42]

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 -
Recurrence at 6 months (%) 1.25 1.25 -

Associations

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