Colon adenocarcinoma


colon adenocarcinoma: An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.

Data source
FinnGen phenocode C3_COLON_ADENO
Cause of Death registry ICD-10: C18, ICD-9: 153, ICD-8: 153
Cancer reg: TOPOGRAPHY codes C18
Cancer reg: MORPHOLOGY codes 8140
Conditions required HLP_C3_COLON_ADENO
Level in the ICD-hierarchy C
First defined in version DF4
DOID 234
GWAS catalog 1001949
MESH D003110

Key figures

Sex All Female Male
Number of individuals 1131 529 602
Unadjusted prevalence (%) 0.65 0.53 0.8
Mean age at first event (years) 66.67 65.96 67.29
Case fatality at 5-years (%) 19.98 19.28 20.6

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 3.79 3.58 3.99


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