Chronic myeloid leukaemia

Description

obsolete_chronic myeloid leukemia: ['Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.']

Data source
FinnGen phenocode C3_CML
Cause of Death registry ICD-10: C92, ICD-9: 204, ICD-8: 204
Cancer reg: TOPOGRAPHY codes C42|C77
Cancer reg: MORPHOLOGY codes 9863
Conditions required HLP_C3_CML
Level in the ICD-hierarchy C
First defined in version DF4
Ontology
DOID 8552
GWAS catalog 0000340
MESH D015464

Key figures

Sex All Female Male
Number of individuals 44 19 25
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 56.02 54.47 57.2
Case fatality at 5-years (%) 13.64 15.79 12.0

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 0.97 - 1.61

Associations

Loading associations…