Acute myeloid leukaemia

Description

acute myeloid leukemia: Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections.

Data source
FinnGen phenocode C3_AML
Cause of Death registry ICD-10: C92, ICD-9: 204, ICD-8: 204
Cancer reg: TOPOGRAPHY codes C42|C77
Cancer reg: MORPHOLOGY codes 9861
Conditions required HLP_C3_AML
Level in the ICD-hierarchy C
First defined in version DF4
Ontology
DOID 9119
GWAS catalog 0000222
MESH D015470
SNOMED CT 91861009

Key figures

Sex All Female Male
Number of individuals 76 30 46
Unadjusted prevalence (%) 0.04 0.03 0.06
Mean age at first event (years) 64.61 61.8 66.45
Case fatality at 5-years (%) 60.53 50.0 67.39

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 13.0 9.52 15.52

Associations

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