Atopic dermatitis, strict definition


atopic eczema: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Data source
FinnGen phenocode ATOPIC_STRICT
Hospital Discharge registry ICD-10: L200, ICD-9: 6918B, ICD-8: 69100
Cause of Death registry ICD-10: L200, ICD-9: 6918B, ICD-8: 69100
First defined in version DF3
DOID 3310
GWAS catalog 0000274
MESH D003876

Key figures

Sex All Female Male
Number of individuals 4055 2779 1276
Unadjusted prevalence (%) 2.33 2.8 1.7
Mean age at first event (years) 27.02 27.47 26.06
Case fatality at 5-years (%) 0.47 0.29 0.86

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 37.04 37.75 35.5


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