Viral infections of the central nervous system

Description

viral meningitis: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)

Data source
FinnGen phenocode AB1_VIRAL_CNS
Hospital Discharge registry ICD-10: A80/A82/A86/A88/A89/A81/A84/A85/A87/A83, ICD-9: 045/046/047/048/049/062/063/064/071, ICD-8: 04[0-3]|06[2-5]|071
Cause of Death registry ICD-10: A82/A86/A88/A89/A81/A84/A85/A87/A83/A80, ICD-9: 045/046/047/048/049/062/063/064/071, ICD-8: 04[0-3]|06[2-5]|071
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 10310
GWAS catalog 1001236
MESH D020805
SNOMED CT 58170007

Key figures

Sex All Female Male
Number of individuals 784 487 297
Unadjusted prevalence (%) 0.45 0.49 0.4
Mean age at first event (years) 39.36 38.4 40.93
Case fatality at 5-years (%) 4.46 2.46 7.74

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 1 1 1
Recurrence at 6 months (%) 10.71 10.88 10.44

Associations

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