Seropositive rheumatoid arthritis

Description

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Data source
FinnGen phenocode RHEUMA_SEROPOS
Include FELTY, RHEUMAT_LUNG, RHEUMA_SEROPOS_OTH, RHEUMA_SEROPOS_WIDE
First defined in version DF2
Ontology
DOID 7148
GWAS catalog 0000685
MESH D001172
SNOMED CT 69896004

Key figures

Sex All Female Male
Number of individuals 3468 2487 981
Unadjusted prevalence (%) 1.99 2.51 1.31
Mean age at first event (years) 54.57 53.72 56.73
Case fatality at 5-years (%) 2.85 2.37 4.08

Longitudinal metrics

Sex All Female Male
Median nb. of events per indiv. 7 7 6
Recurrence at 6 months (%) 74.74 75.19 73.6

Associations

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